Invasive Pneumococcal Disease in Children Can Reveal a Primary Immunodeficiency
نویسندگان
چکیده
منابع مشابه
Invasive pneumococcal disease in children can reveal a primary immunodeficiency.
BACKGROUND About 10% of pediatric patients with invasive pneumococcal disease (IPD) die from the disease. Some primary immunodeficiencies (PIDs) are known to confer predisposition to IPD. However, a systematic search for these PIDs has never been carried out in children presenting with IPD. METHODS We prospectively identified pediatric cases of IPD requiring hospitalization between 2005 and 2...
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BACKGROUND Recurrent invasive pneumococcal disease (rIPD) occurs mostly in children with an underlying disease, but some cases remain unexplained. Immunodeficiency has been described in children with rIPD, but the prevalence is unknown. We used a nationwide registry of all laboratory-confirmed cases of rIPD to identify cases of unexplained rIPD and examine them for immunodeficiency. METHODS C...
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ژورنال
عنوان ژورنال: PEDIATRICS
سال: 2014
ISSN: 0031-4005,1098-4275
DOI: 10.1542/peds.2014-1817dddd